Jonas Edward Salk was born
on October 28, 1914 in New York City. His parents, who were uneducated,
were determined to help Salk succeed in school and they were very encouraging
throughout his life. He was the first in their family to attend college.
He started at City College of New York with the intention of studying law,
however he quickly became interested in medicine and science. He went on
to medical school at New York University and there, in 1938, he began working
with microbiologist Thomas Francis, Jr., who was looking for an influenza
vaccine. Working together they developed one that was used for the army
during World War II.
Salk began his immunology
research in 1938 at New York University and he later participated in a
program at the University of Pittsburgh to identify the known strains of
polio virus. While at the University of Pittsburgh, with the National Foundation
for Infantile Paralysis, gave Salk the opportunity to study polio
and work to develop a vaccine against polio.
Polio, or poliomythelitis,
is a very dangerous virus.Viruses reproduce by
invading healthy cell, doing this forces the cell to produce more virus
resulting in the cells death. Although its just microscopic,
the virus known as
polio, can cause life long paralysis and sometimes even death. Those
who survive polio can end up being severely crippled for the rest of their
lives.
Salk devoted the next eight
years to studying polio and working to find an
effective and safe vaccine. Salk grew the virus with tissue cells in
bottles and
then killed them with formaldehyde. This “killed” virus mixture had
the ability
to immunize without the risk of infecting the patient. The vaccine
proved
effected and it was tested nationally starting in 1954. The trial included
1,
829,916 children, and the vaccine proved to be 70 to 90 percent effective
against the disease. Shortly after the trial the vaccine was being
used widely
around the world and the threat of polio became very small compared
to what it
had been before the vaccine.
When the news of the discovery
got around the world Salk was known as a
“miracle worker”. He also refused to patent the vaccine because he
didn’t want
to profit personally from it, he only wanted it to help people. He
relieved a
Congressional Gold Medal for his “great achievement in the field
of medicine.”
Salk’s vaccine was replaced
quickly by a variation developed by Albert Sabin that could be taken orally.
The oral one became popular very quickly and Salk's was used very less
often. Unlike Salk’s vaccine, Sabin’s was made from “live” polio virus,instead
of “killed” virus, however the cases of polio reported after that were
a result of the “live” polio virus in the vaccine. Salk’s Vaccine
has begun to replace Sabin's in places like the United States.
In 1963 Salk founded the
Jonas Salk Institute for Biological studies in LaJolla California, which
was used for medical and science related research. He resigned at the University
of Pittsburgh to work full time at the Institute and he continued to study
infectious disease. Salk also went on to write books and work with his
sons, who were also studying medicine and science. He remained the director
of the Institute until his death.
Jonas Salk spent his last
years searching for a vaccine against AIDS. Jonas Salk died on June
23, 1995. He was 80 years old. Salk is best known for
developing he first successful vaccine for polio, however he also made
significant contributions to our understanding of influenza and other
infectious
diseases.
Bibliography
Travers, Bridget. World of Scientific Discovery. Scientific Milestones
and the
People who Made Them Possible. Detroit: Gale Research Inc., 1994.
Robbins, Dr. Fred. “The Quest For A Vaccine.” World Health Jan-Feb
1995: 14- 15.
“American Physician and Research Scientist.” www.bena.com/lucidcafe/library/95oct/jesalk.html.
“Jonas Salk”. http://edweb.sdsu.edu/SDHS/bio/salk.htm.